What You Should to Know About Facial Angiofibromas

Facial Angiofibromas are benign cutaneous tumors. When they are multiple and have a symmetrical distribution on face, involving the cheeks, nasolabial folds and chin, angiofibromas are a hallmark of tuberous sclerosis complex (TSC or Bourneville disease) .

Multiple facial angiofibromas are also found a sign of Birt-Hogg-Dubé syndrome (BHD) and multiple endocrine neoplasia type 1.
Facial angiofibromas affect equally both men and women.

Clinical Presentation

Angiofibromas are small, solitary, dome-shaped, skin-colored or red papules is the classic presentation of facial angiofibromas. On the surface of the papule, we can see little telangiectatic vessels.
They're most commonly found on the central face, around the nose, and on the malar eminences. Lesions may bleed, alter the vision, and cause emotional stress
Pearly penile papules are little papules that are pearly white, dome-shaped, and densely aggregated on the head of the penis in like a corona.
Periungual Angiofibromas appear in early adulthood, on the lateral and the proximal nail fold. They can be painful. They cause a nail to be distorted.
Oral fibromas occur on the gingiva, buccal and labial mucosa and the tongue (rare).

Angiofibroma is diagnosed using a combination of history, physical examination, and skin biopsy. If you suspect that your patients have Tuberous sclerosis complex, MEN-1, or Birt-Hogg-Dube, you should get genetic testing done as well as a thorough workup to look for malignancies related to those illnesses.

Multiple Facial angiofibromas don't improve spontaneously.
For the disfiguring, patients demand usually to be treated. There are many options for the treatment of facial angiofibroma
Destructive approaches such as dermabrasion, surgical excision, and laser therapy.
Recentely, several studies cited that topical rapamycin can be an effective treatment for facial angiofibroma associated with Tuberous Sclerosis.

Facial angiofibromas are benign tumors presenting as dome-shaped, firm, pink papules on the nose and adjoining central face.